PURPOSE: To compare the posterior capsule opasification (PCO) prevention effect of two intraocular lenses, different in design and material. SETTING: Regional T.I. Eroshevsky Ophthalmic Hospital, State Medical University, Samara, Russian Federation. METHODS: We compared PCO development after implantation of two different IOLs. 121 eye was implanted with hydrophobic three-piece AcrySof MA30AC (Alcon) and 143 with hydrophilic single-piece Centerflex 570H (Rayner). The follow-up time was 24 months. RESULTS: Central and peripheral PCO rates were 0,276 and 0,402 for Acrysof and 0,431 and 0,933 for Centerflex, respectively. Different kinds of PCO (cells, fibrosis, folds) were observed in 26%, 66% и 19% in Acrysof group versus 72%, 59% и 10% in Centerflex group. Difference in visual acuity and capsulotomy rate was not statisticaly significant. PCO prevalence at the place of optic-haptic junction was more prominent in Centerflex eyes (69%) vs. 24% in Acrysof group. PCO in areas of weak IOL-capsular contact appeared in 17% in Centerflex group and in 11% in Acrysof group. IOL centration was better for Centerflex. CONCLUSION: Lack of square edge in optic-haptic junction is the main factor in development of cellular PCO. Slim PMMA haptic facilitates capsular distortion (PC folds & pleats) and IOL decentration. Hydrophobic IOL material may inhibit cell component of PCO.
G. Krainov, A. Zolotaryov, I. Malov, RUSSIA